stubborn_ass ([personal profile] stubborn_ass) wrote in [personal profile] ecosophia 2025-05-16 02:08 am (UTC)

Big pharma / Biotech regulatory changes coming? Plus vim vignettes

Karl Denniger had a good take: https://market-ticker.org/akcs-www?post=253263

"A Note On Biotechs

There's a rather interesting thing that's happened in the sector -- across the sector -- since Trump's inauguration.

Stock prices in the sector have crashed; with many names down 50% or more, even among those firms with drugs that are in the approval pipeline with published positive results (that is, awaiting final FDA review.)

This is not the sort of thing you'd expect in a marketplace where reported results from trials are objectively correct. Certainly those firms with a dubious early record that are a "close" judgment call on their particular drugs being developed are one thing; it is the truth that most drug investigations fail.

But this is something different entirely in that the drubbings are pretty-much across-the-board.

This implies that the public markets are saying that the former way of doing business resulted in firms with drugs that were less than honestly reported as to results, or which were approved and thus the companies made money on them despite them not working or perhaps being unsafe."

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One of the comments noted that even after approval, perhaps 4 out of 10 biotech drugs get pulled from the market when the side effects become too obvious to ignore. So people have been aware of the fraud going on , but FDA had been turning a blind eye and allowed the biotech firms to make some bank before telling them to pull the drugs.

Another comment noted that the new Arkansas law allowing over the counter VIM sales is no real biggie. It has been legally approved in Tennesee for a while, yet in reality the big chain pharmacies in Tn still refuse to sell VIM OTC, and the private pharmacies do price-gouging. So still better and more effective to rely on 'animal' supplies. That was interesting on the ground news to me.

Another comment pointed out that since even really high dose of VIM is not toxic, it means people using accidentally super high animal doses should be fine. Notice that MSM has kept surreptiously quiet about horse paste poisoning for quite a while now? Aka if there was even 1 real case, they would have blared about it 24/7. I find the whole situation irony... coz if people do end up end up taking higher doses then intended, they usually end up resolving other long-term issues unexpectedly.

Small anec-data - my wife is Type 2 diabetic... about 70kg and takes 5ml of liquid VIM + HCQ for just over a month. Her blood sugar numbers are now routinely in the high normal range (6's)... and if she takes the more natural supplements (berberine, curcumin), it can get to mid 5's. Even without exercise.... I'd ask her to curtail her daily walks/runs for a few days just to confirm that the effects is independant of exercise levels.

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